Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2267607 | 0.80 | ALDH1A1 (0.44) | CNR1RAB9AALDH1A1HPGDTSHR | |
| SCHEMBL3500221 | 0.80 | ALDH1A1 (0.70) | RAB9AALDH1A1HPGDTSHRL3MBTL1 | |
| SCHEMBL1900249 | 0.80 | ALDH1A1 (0.44) | CNR1RAB9AALDH1A1HPGDTSHR | |
| SCHEMBL286332 | 0.79 | ALDH1A1 (0.63) | CNR1RAB9ARECQLALDH1A1HPGD | |
| SCHEMBL211358 | 0.79 | RXFP1 (0.50) | CNR1RAB9ARECQLALDH1A1HPGD | |
| SCHEMBL27564565 | 0.78 | ALDH1A1 (0.67) | RAB9AALDH1A1HPGDTSHRL3MBTL1 | |
| Bromide SCHEMBL6121613 | 0.77 | SMN1; SMN2 (0.49) | CNR1RAB9ARECQLALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9528992 | 0.77 | ALDH1A1 (0.61) | CNR1RAB9ARECQLALDH1A1HPGD | |
| SCHEMBL423145 | 0.77 | RAB9A (0.47) | CNR1RAB9ARECQLALDH1A1HPGD | |
| SCHEMBL1477812 | 0.77 | RAB9A (0.47) | CNR1RAB9ARECQLALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380767-A | Thiazole amide compound containing diphenylamino group and preparation method and application thereof | 安徽理工大学 | 2022-04-22 | — | — | CN | claimed |
| CN-113387926-B | Heterocyclic carboxylic ester compound and application thereof as herbicide | 沈阳中化农药化工研发有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-114380767-A | Thiazole amide compound containing diphenylamino group and preparation method and application thereof | 安徽理工大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-113387926-A | Heterocyclic carboxylic ester compound and application thereof as herbicide | 沈阳中化农药化工研发有限公司 | 2021-09-14 | — | — | CN | disclosed |
| EP-3159341-B1 | PYRIDINO[1,2-A]PYRIMIDONE ANALOGUE USED AS PI3K INHIBITOR | CHAI TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2019-08-21 | — | — | EP | disclosed |
| EP-3159341-B1 | PYRIDINO[1,2-A]PYRIMIDONE ANALOGUE USED AS PI3K INHIBITOR | CHAI TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2019-08-21 | — | — | EP | disclosed |
| CN-105461711-B | Pyrido [1,2-a] pyrimidinone analogues as PI3K inhibitor | 正大天晴药业集团股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-106470992-B | Pyrido [1,2-A] pyrimidinone analogues as PI3K inhibitor | 正大天晴药业集团股份有限公司 | 2018-11-06 | — | — | CN | disclosed |
| US-20180029991-A1 | AMIDE COMPOUND AND THE PREPARATION METHOD AND USE THEREOF | Shenyang Sinochem Agrochemicals R&D Co., LTD (CN) | 2018-02-01 | — | — | US | disclosed |
| US-9856256-B2 | Pyridino[1,2-A]pyrimidone analogue used as P13K inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2018-01-02 | — | — | US | disclosed |
| CN-1157287-A | Arylalkyl diazinones | MERCK PATENT GMBH (DE) | 1997-08-20 | — | — | CN | disclosed |
| EP-0292937-B1 | Amide derivatives, and their production and agricultural fungicides containing them | SUMITOMO CHEMICAL CO (JP) | 1994-08-10 | — | — | EP | disclosed |
| EP-0313091-B1 | AMIDE DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF, AND AGRICULTURAL-HORTICULTURAL FUNGICIDE CONTAINING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5136042-A | PROCESS FOR THE PREPARATION OF THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-08-04 | — | — | US | disclosed |
| US-5104886-A | Syntergistic mixtures of amide substituted thiazoles and other fungicides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-04-14 | — | — | US | disclosed |
| US-4980363-A | CONTROLLING PLANT DISEASES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0377750-A1 | PROCESS FOR PREPARING THIAZOLECARBOXYLIC ACID CHLORIDES | MITSUI CHEMICALS, INC. (JP) | 1990-07-18 | — | — | EP | disclosed |
| US-4918089-A | THIAZOLE DERIVATIVES; CURATIVE, NONPHYTOTOXIC | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0313091-A2 | Amide derivatives, processes for production thereof, and agricultural-horticultural fungicide containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-04-26 | — | — | EP | disclosed |
| EP-0292937-A1 | Amide derivatives, and their production and agricultural fungicides containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180029991-A1 | AMIDE COMPOUND AND THE PREPARATION METHOD AND USE THEREOF | CYP51A1, ERG28, NAT1 | CNR1 1671/4885RAB9A 1568/4885RECQL 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.