Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926229 | 0.85 | ALOX15 (0.55) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2341919 | 0.82 | AKR1C3 (0.70) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30564458 | 0.82 | AKR1C3 (0.70) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1492942 | 0.82 | AKR1C3 (0.70) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28359064 | 0.81 | ALDH1A1 (0.51) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28301104 | 0.81 | OGA (0.42) | ALDH1A1SMN1; SMN2NPC1MAPTKMT2A | |
| SCHEMBL19926091 | 0.79 | ALOX15 (0.58) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10631845 | 0.79 | AKR1C3 (0.50) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14320091 | 0.79 | AKR1C3 (0.53) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2699086 | 0.79 | AKR1C3 (0.53) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105681-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | LASSOIE MARIE-AGNES | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105681-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | SCN4A, NECTIN4, VPS4B | AKR1C3 3560/4885AKR1C2 3238/4885ALDH1A1 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.