Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 6/20 | 0.60 |
| ▸ | SI | P14410 | 6/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343111 | 0.89 | MAPT (0.69) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL30040360 | 0.89 | MAPT (0.69) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL10717194 | 0.85 | NR3C1 (0.73) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL18364667 | 0.83 | MAPT (0.54) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL18364660 | 0.83 | GPR84 (0.56) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL24145185 | 0.83 | NR3C1 (0.57) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL3495495 | 0.83 | GUSB (0.61) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL31511311 | 0.83 | NR3C1 (0.57) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL3493350 | 0.83 | GUSB (0.58) | NR3C1PGRNR3C2ARMGAM | |
| SCHEMBL29540078 | 0.83 | GUSB (0.61) | NR3C1PGRNR3C2ARMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042657-A1 | USE OF DIINDOLYLMETHANE (DIM) COMPOUNDS AND DERIVATIVES AS NEUROPROTECTIVE AGENTS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-15 | — | — | WO | claimed |
| US-20100087504-A1 | Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-08 | — | — | US | claimed |
| US-20210024499-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | XIAMEN UNIVERSITY (CN) | 2021-01-28 | — | — | US | disclosed |
| WO-2019183527-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-09-26 | — | — | WO | disclosed |
| US-8580843-B2 | Use of diindolylmethane (DIM) compounds and derivatives as neuroprotective agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580843-B2 | Use of diindolylmethane (DIM) compounds and derivatives as neuroprotective agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580843-B2 | Use of diindolylmethane (DIM) compounds and derivatives as neuroprotective agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-11-12 | — | — | US | disclosed |
| WO-2010042657-A1 | USE OF DIINDOLYLMETHANE (DIM) COMPOUNDS AND DERIVATIVES AS NEUROPROTECTIVE AGENTS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010042657-A1 | USE OF DIINDOLYLMETHANE (DIM) COMPOUNDS AND DERIVATIVES AS NEUROPROTECTIVE AGENTS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-15 | — | — | WO | disclosed |
| US-20100087504-A1 | Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-08 | — | — | US | disclosed |
| US-20100087504-A1 | Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-08 | — | — | US | disclosed |
| US-20100087504-A1 | Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087504-A1 | Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents | AIFM1, NLN, SNCA | NR3C1 2043/4885PGR 3216/4885NR3C2 2843/4885 |
| US-20210024499-A1 | OXIDIZED BIS(3-INDOLYL)METHANES AND USES THEREOF | BCL2, BCOR, BCLAF1 | NR3C1 71/4885PGR 893/4885NR3C2 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.