Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344813 | 0.75 | GRIN2D (0.38) | MEN1KMT2AGAASMN1; SMN2PLAUR | |
| SCHEMBL3349055 | 0.75 | CHRM2 (0.40) | MEN1KMT2AGAASMN1; SMN2PLAUR | |
| SCHEMBL3299360 | 0.75 | L3MBTL1 (0.42) | MEN1KMT2AGAASMN1; SMN2PLAUR | |
| SCHEMBL9921703 | 0.67 | SMN1; SMN2 (0.45) | MEN1KMT2AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4840749 | 0.66 | GAA (0.41) | MEN1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL11319209 | 0.66 | CXCR4 (0.41) | ALDH1A1TSHRCYP1A2CYP2D6KCNA5 | |
| SCHEMBL3301918 | 0.66 | ADORA1 (0.46) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL3301341 | 0.66 | ALDH1A1 (0.39) | MEN1KMT2AGAASMN1; SMN2PLAUR | |
| SCHEMBL25649146 | 0.66 | MEN1 (0.35) | MEN1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL3345196 | 0.65 | MAOB (0.43) | MEN1KMT2AGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045015-A1 | HETEROARYL SUBSTITUTED THIENO[2,3-D]PYRIMIDINE AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |