SCHEMBL3344912

SCHEMBL3344912

C=CCOC1O[C@H](C)[C@@H](OCCCCC)[C@H]1OCCCCC

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 5/20 0.38
FGF1 P05230 3/20 0.32
FGF2 P09038 3/20 0.32
VEGFA P15692 3/20 0.32
HPSE Q9Y251 3/20 0.32
TNF P01375 1/20 0.32
SLC2A1 P11166 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3344916 1.00 GBA1 (0.38) GBA1FGF1FGF2VEGFAHPSE
SCHEMBL6574204 0.85 GBA1 (0.46) GBA1FGF1FGF2VEGFAHPSE
SCHEMBL6574209 0.85 GBA1 (0.46) GBA1FGF1FGF2VEGFAHPSE
SCHEMBL8992926 0.85 GBA1 (0.46) GBA1FGF1FGF2VEGFAHPSE
SCHEMBL3345071 0.80 GJB2 (0.41) GBA1FGF1FGF2VEGFAHPSE
SCHEMBL3345069 0.80 GJB2 (0.41) GBA1FGF1FGF2VEGFAHPSE
SCHEMBL8992782 0.79 TNF (0.46) GBA1FGF1FGF2VEGFAHPSE
SCHEMBL8992784 0.79 TNF (0.46) GBA1FGF1FGF2VEGFAHPSE
SCHEMBL7594906 0.75 ALDH1A1 (0.36) GBA1TNF
SCHEMBL12480998 0.75 SLC2A1 (0.40) GBA1TNFSLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101595117-B Method for production of furanose derivative API CORP 2014-01-22 CN disclosed
US-8394935-B2 Method for producing furanose derivative API CORPORATION (JP) 2013-03-12 US disclosed
US-8394935-B2 Method for producing furanose derivative API CORPORATION (JP) 2013-03-12 US disclosed
US-20100105890-A1 METHOD FOR PRODUCING FURANOSE DERIVATIVE API CORPORATION (JP) 2010-04-29 US disclosed
US-20100105890-A1 METHOD FOR PRODUCING FURANOSE DERIVATIVE API CORPORATION (JP) 2010-04-29 US disclosed
EP-2105445-A1 METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE API Corporation (JP) 2009-09-30 EP disclosed
EP-2105445-A1 METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE API Corporation (JP) 2009-09-30 EP disclosed
WO-2008069303-A1 METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE API CORPORATION (JP) 2008-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105890-A1 METHOD FOR PRODUCING FURANOSE DERIVATIVE DERA, ALDOA, DPYD GBA1 1692/4885FGF1 1862/4885FGF2 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.