Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12607804 | 0.93 | PRMT5 (0.52) | DPP4DPP8PRMT5WDR77OPRM1 | |
| Trifluoroacetic Acid SCHEMBL1791141 | 0.86 | OPRM1 (0.54) | PRMT5WDR77OPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL1786436 | 0.80 | ENPP2 (0.47) | DPP4DPP7DPP8DPP9PRMT5 | |
| SCHEMBL3345252 | 0.80 | NAMPT (0.47) | PRMT5WDR77DRD3HTR1AHTR2B | |
| SCHEMBL12607826 | 0.79 | OPRM1 (0.59) | PRMT5WDR77OPRM1OPRD1OPRK1 | |
| SCHEMBL12607818 | 0.77 | TMEM97 (0.62) | PRMT5WDR77OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL1785554 | 0.76 | TMEM97 (0.61) | PRMT5WDR77OPRM1OPRD1OPRK1 | |
| Trifluoroacetic Acid SCHEMBL1783579 | 0.75 | DPP4 (0.45) | DPP4DPP7DPP8DPP9PRMT5 | |
| SCHEMBL3699858 | 0.73 | OPRM1 (0.68) | OPRM1OPRD1OPRK1DRD3DRD2 | |
| SCHEMBL12607816 | 0.72 | ENPP2 (0.52) | PRMT5WDR77OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323487-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | GLAXOSMITHKLINE LLC | 2014-10-30 | — | — | US | disclosed |
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | IGNAR DIANE MICHELE | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | OPRL1, OPRD1, OPRK1 | DPP4 1431/4885DPP7 1333/4885DPP8 2313/4885 |
| US-20140323487-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | OPRL1, OPRM1, OPRK1 | DPP4 1228/4885DPP7 1096/4885DPP8 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.