Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PAICS | P22234 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786352 | 0.93 | OPRM1 (0.44) | CCR6HDAC1HDAC8HDAC6FLT1 | |
| Trifluoroacetic Acid SCHEMBL3338278 | 0.87 | OPRM1 (0.50) | CCR6HDAC1DPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL3340025 | 0.86 | OPRM1 (0.47) | CCR6DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL3339102 | 0.85 | HDAC1 (0.52) | CCR6HDAC1HDAC8HDAC6FLT1 | |
| Trifluoroacetic Acid SCHEMBL3345314 | 0.85 | OPRM1 (0.45) | CCR6DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL3339667 | 0.84 | DPP4 (0.42) | CCR6HDAC6DPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL3337465 | 0.84 | DPP4 (0.42) | CCR6HDAC6DPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL3340014 | 0.84 | CTSC (0.44) | CCR6DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL16194723 | 0.83 | DPP4 (0.42) | CCR6DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL3345276 | 0.82 | OPRM1 (0.40) | CCR6HDAC6DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323487-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | GLAXOSMITHKLINE LLC | 2014-10-30 | — | — | US | disclosed |
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | IGNAR DIANE MICHELE | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | OPRL1, OPRD1, OPRK1 | CCR6 1700/4885HDAC1 1478/4885HDAC8 1607/4885 |
| US-20140323487-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | OPRL1, OPRM1, OPRK1 | CCR6 779/4885HDAC1 2440/4885HDAC8 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.