SCHEMBL3345351

SCHEMBL3345351

COCO[Si](CCCc1ccccc1)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SIGMAR1 Q99720 3/20 0.36
MAOA P21397 1/20 0.36
CES1 P23141 1/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
OPRM1 P35372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1968087 0.90 TDP1 (0.38) KDM4ELMNAL3MBTL1ALDH1A1KCNH2
SCHEMBL2822247 0.86 IDO1 (0.45) IDO1L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL28066220 0.83 IDO1 (0.38) IDO1L3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL9167165 0.83 IDO1 (0.38) IDO1L3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL8161394 0.83 MAOA (0.44) IDO1MAOAAOC3
SCHEMBL3345563 0.82 CES1 (0.38) IDO1KDM4ELMNAL3MBTL1MEN1
SCHEMBL2748794 0.80 L3MBTL1 (0.47) IDO1L3MBTL1SIGMAR1MAOA
SCHEMBL18979278 0.79 L3MBTL1 (0.49) L3MBTL1SIGMAR1MAOACES1
SCHEMBL16293300 0.79 L3MBTL1 (0.49) L3MBTL1SIGMAR1MAOACES1
SCHEMBL9395958 0.79 L3MBTL1 (0.49) L3MBTL1SIGMAR1MAOACES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151188-A1 STRUCTURE HAVING ORGANIC-INORGANIC COMPOSITE LAYER AND METHOD OF MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2010-06-17 US disclosed
US-20090239086-A1 MICROPHASE-SEPARATED STRUCTURE ON FLEXIBLE SUBSTRATE, AND METHOD OF MANUFACTURE THEREOF FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed