SCHEMBL3345563

SCHEMBL3345563

COCO[Si](C)(CCCc1ccccc1)OC

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.38
IDO1 P14902 1/20 0.37
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
FAAH O00519 1/20 0.36
DAGLA Q9Y4D2 1/20 0.35
SIGMAR1 Q99720 2/20 0.35
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1068905 0.86 IDO1 (0.44) CES1IDO1L3MBTL1MEN1KMT2A
SCHEMBL3345351 0.82 IDO1 (0.38) CES1IDO1KDM4ELMNAL3MBTL1
SCHEMBL6325307 0.81 CES1 (0.46) CES1IDO1L3MBTL1FAAHSIGMAR1
SCHEMBL13735990 0.81 CHRM2 (0.39) CES1IDO1L3MBTL1MEN1KMT2A
SCHEMBL1067547 0.76 CHRM2 (0.43) IDO1L3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL3342170 0.75 IDO1 (0.44) CES1IDO1L3MBTL1MEN1KMT2A
SCHEMBL1584725 0.75 TDP1 (0.44) CES1IDO1L3MBTL1
SCHEMBL1968087 0.75 TDP1 (0.38) KDM4ELMNAL3MBTL1
SCHEMBL2584078 0.74 IDO1 (0.47) IDO1L3MBTL1MEN1KMT2ASIGMAR1
SCHEMBL9716586 0.73 MAOA (0.48) IDO1L3MBTL1MEN1KMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100151188-A1 STRUCTURE HAVING ORGANIC-INORGANIC COMPOSITE LAYER AND METHOD OF MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2010-06-17 US disclosed