Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL3345470

O=S(=O)(O)C(F)(F)F.Oc1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
CA12 O43570 1/20 0.52
GLA P06280 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA14 Q9ULX7 1/20 0.52
PTPN1 P18031 2/20 0.43
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.41
CA5A P35218 1/20 0.40
ESR1 P03372 6/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
ALDH1A1 P00352 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL29657724 1.00 CA1 (0.52) CA1CA2CA9TDP1CA12
Trifluoromethanesulfonic Acid SCHEMBL9470710 1.00 CA1 (0.52) CA1CA2CA9TDP1CA12
Trifluoromethanesulfonic Acid SCHEMBL576036 0.87 LMNA (0.52) CA1CA2CA9CA12CA3
Trifluoromethanesulfonic Acid SCHEMBL1712877 0.85 CA2 (0.53) CA1CA2CA9TDP1CA12
Biphenyl SCHEMBL1050411 0.83 PTPN1 (0.58) CA1CA2CA9CA12PTPN1
Phenol SCHEMBL8573408 0.82 TDP1 (0.61) CA1CA2CA9TDP1CA12
Phenol SCHEMBL138896 0.82 TDP1 (0.69) CA1CA2CA9TDP1CA12
Phenol SCHEMBL8801033 0.82 TDP1 (0.69) CA1CA2CA9TDP1CA12
Phenol SCHEMBL4576632 0.82 TDP1 (0.69) CA1CA2CA9TDP1CA12
Phenol SCHEMBL28121724 0.82 TDP1 (0.69) CA1CA2CA9TDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110903316-B Phosphonate compound and preparation method and application thereof 中南大学 2021-03-02 CN claimed
CN-110903316-A Phosphonate compound and preparation method and application thereof 中南大学 2020-03-24 CN claimed
CN-101503387-B Preparation of 3-aryl substituted indole containing ester group at 2 site UNIV ZHEJIANG 2011-06-15 CN claimed
CN-101503387-A Preparation of 3-aryl substituted indole containing ester group at 2 site UNIV ZHEJIANG (CN) 2009-08-12 CN claimed
CN-115368223-B Hydroxy aryl ketone and synthesis method thereof 中国石油化工股份有限公司 2025-03-04 CN disclosed
CN-115197087-B Polysubstituted cyclobutene derivative and preparation method thereof 华东师范大学 2024-05-17 CN disclosed
CN-115368223-A Hydroxy arone and synthesis method thereof 中国石油化工股份有限公司 2022-11-22 CN disclosed
CN-115197087-A Polysubstituted cyclobutene derivatives and process for preparing same 华东师范大学 2022-10-18 CN disclosed
CN-114163379-A Fluorocarbazolyl diphenylethylene biphenyl compound and preparation method and application thereof 闽都创新实验室 2022-03-11 CN disclosed
CN-110903316-B Phosphonate compound and preparation method and application thereof 中南大学 2021-03-02 CN disclosed
CN-110903316-A Phosphonate compound and preparation method and application thereof 中南大学 2020-03-24 CN disclosed
US-10266503-B1 Sulfoxide ligand metal catalyzed oxidation of olefins THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2019-04-23 US disclosed
US-5204344-A (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes MERCK FROSST CANADA, INC. (CA) 1993-04-20 US disclosed
EP-0535924-A1 (Bicyclic-azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1993-04-07 EP disclosed
EP-0535923-A1 (Azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1993-04-07 EP disclosed
EP-0535926-A1 (Hetero-arylmethoxy) indoles as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1993-04-07 EP disclosed
EP-0535925-A1 (Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1993-04-07 EP disclosed
US-5190968-A Antiinflammatory MERCK FROSST CANADA, INC. (CA) 1993-03-02 US disclosed
WO-1992010096-A1 COMPOUNDS THAT INHIBIT COMPLEMENT AND/OR SUPPRESS IMMUNE ACTIVITY T CELL SCIENCES, INC. (US) 1992-06-25 WO disclosed
EP-0490587-A1 Substituted pyrazolopyrimidines and imidazopyridazines as angiotensin II antagonists MERCK & CO. INC. (US) 1992-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10266503-B1 Sulfoxide ligand metal catalyzed oxidation of olefins YAP1, ICOSLG, SPIN3 CA1 3255/4885CA2 3802/4885CA9 3833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.