Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28886890 | 0.82 | LTA4H (0.44) | LTA4HPPARAKDM4EMAPTPPARG | |
| SCHEMBL7040229 | 0.80 | LTA4H (0.57) | LTA4HKDM4EALDH1A1TAAR1NPC1 | |
| SCHEMBL3906600 | 0.80 | LTA4H (0.57) | LTA4HKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL30747866 | 0.78 | IDO1 (0.56) | IDO1IDO2NR1H2NR1H3PPARA | |
| SCHEMBL5925309 | 0.77 | LTA4H (0.54) | LTA4HKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL5925318 | 0.76 | LTA4H (0.53) | LTA4HKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL477614 | 0.76 | LTA4H (0.61) | LTA4HKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6028964 | 0.76 | LTA4H (0.61) | LTA4HKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL3780733 | 0.76 | LTA4H (0.61) | LTA4HKDM4EALDH1A1GAAMAPT | |
| SCHEMBL4846964 | 0.76 | LTA4H (0.61) | LTA4HKMT2AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045013-A1 | PHENYL SUBSTITUTED THIENO [2,3-D] PYRIMIDINES AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |