Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | MST1R | Q04912 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3906600 | 0.85 | LTA4H (0.57) | LTA4HDPP4MAPTKDM4EALDH1A1 | |
| SCHEMBL5477977 | 0.83 | LTA4H (0.47) | LTA4HDPP4PDCD1CD274MAPT | |
| SCHEMBL5925309 | 0.82 | LTA4H (0.54) | LTA4HDPP4MAPTKDM4EALDH1A1 | |
| SCHEMBL11065500 | 0.82 | PDCD1 (0.56) | LTA4HDPP4PDCD1CD274MAPT | |
| SCHEMBL20655986 | 0.82 | DPP4 (0.47) | LTA4HDPP4MAPTKDM4EALDH1A1 | |
| SCHEMBL5925318 | 0.80 | LTA4H (0.53) | LTA4HDPP4MAPTKDM4EALDH1A1 | |
| SCHEMBL3780733 | 0.80 | LTA4H (0.61) | LTA4HDPP4CYP2A6MAPTKDM4E | |
| SCHEMBL20656009 | 0.80 | DPP4 (0.46) | LTA4HDPP4MAPTKDM4EALDH1A1 | |
| SCHEMBL6028964 | 0.80 | LTA4H (0.61) | LTA4HDPP4MAPTKDM4EALDH1A1 | |
| SCHEMBL4846964 | 0.80 | LTA4H (0.61) | LTA4HDPP4MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387799-A | Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof | 南京工业大学 | 2021-09-14 | — | — | CN | claimed |
| CN-114394922-B | Preparation method of N-substituted pyrrolyl aryl propenone compound | 河南农业大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-114394922-A | Preparation method of N-substituted pyrrolyl aryl propenone compound | 河南农业大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-113387799-B | Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof | 南京工业大学 | 2021-12-21 | — | — | CN | disclosed |
| CN-113387799-A | Preparation method of gamma, gamma-diaryl ester or gamma, gamma-triaryl ester compound and product thereof | 南京工业大学 | 2021-09-14 | — | — | CN | disclosed |
| US-20200165266-A1 | RING CLOSURE REACTION | FLEXENABLE LIMITED (GB) | 2020-05-28 | — | — | US | disclosed |
| WO-2019011826-A1 | RING CLOSURE REACTION | MERCK PATENT GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |
| US-8563786-B2 | Method for producing optically active alcohol | MITSUI CHEMICALS, INC. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20130225583-A1 | SUBSTITUTED AMINO-TRIAZOLYL PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. | 2013-08-29 | — | — | US | disclosed |
| EP-2629616-A2 | SUBSTITUTED AMINO-TRIAZOLYL PDE10 INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012054366-A2 | SUBSTITUTED AMINO-TRIAZOLYL PDE10 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-04-26 | — | — | WO | disclosed |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-04-12 | — | — | US | disclosed |
| EP-2412694-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | Mitsui Chemicals, Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
| EP-0988285-B1 | PRODRUG FORMS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | VION PHARMACEUTICALS INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-0988285-A4 | PRODRUG FORMS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | VION PHARMACEUTICALS INC (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-0988285-A1 | PRODRUG FORMS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | Vion Pharmaceuticals, Inc. (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998051669-A1 | PRODRUG FORMS OF RIBONUCLEOTIDE REDUCTASE INHIBITORS 3-AP AND 3-AMP | VION PHARMACEUTICALS, INC. (US) | 1998-11-19 | — | — | WO | disclosed |
| US-5767134-A | Prodrug forms of ribonucleotide reductase inhibitors 3-AP and 3-AMP | VION PHARMACEUTICALS, INC. (US) | 1998-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165266-A1 | RING CLOSURE REACTION | LIG4, ATG7, RNF4 | LTA4H 1752/4885DPP4 3055/4885PDCD1 1599/4885 |
| US-20130225583-A1 | SUBSTITUTED AMINO-TRIAZOLYL PDE10 INHIBITORS | PDE10A, PDE12, PDE4A | LTA4H 2126/4885DPP4 268/4885PDCD1 3100/4885 |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | ADH1A, ADH1C, FHIT | LTA4H 2533/4885DPP4 4214/4885PDCD1 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.