Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345079 | 0.85 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3348773 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3347965 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL3344676 | 0.82 | TDP1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3348700 | 0.82 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3346093 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL3345108 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3344656 | 0.78 | TP53 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL3345122 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL3777108 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |