Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351444 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3348773 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3773003 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3349098 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3345079 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3346540 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3347965 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3345539 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3344710 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL3348700 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |