Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3351499 | 0.89 | CNR1 (0.37) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL3346117 | 0.88 | DDB1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL3344676 | 0.87 | TDP1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3345079 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3345539 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3348099 | 0.80 | HPGD (0.41) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL3348773 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10PKM | |
| SCHEMBL3347965 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL3409928 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL3344656 | 0.78 | TP53 (0.41) | ALDH1A1HPGDKDM4EHSD17B10CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |