Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 5/20 | 0.44 |
| ▸ | PPIF | P30405 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13424800 | 0.89 | NPC1 (0.42) | PPIAPPIFCYP19A1KMT2AMAPT | |
| SCHEMBL3345989 | 0.86 | PPIA (0.49) | PPIAPPIFCYP19A1KMT2AMEN1 | |
| SCHEMBL3352619 | 0.83 | PPIA (0.41) | PPIAMAPT | |
| SCHEMBL15156975 | 0.74 | LMNA (0.60) | KMT2AMEN1MAPTHTT | |
| SCHEMBL7965575 | 0.72 | PPIA (0.50) | PPIAPPIFCYP19A1KMT2AMEN1 | |
| SCHEMBL13424801 | 0.72 | NPC1 (0.43) | MAPTHTT | |
| SCHEMBL13424802 | 0.72 | KDM4E (0.40) | KMT2AMAPTHTT | |
| SCHEMBL3345345 | 0.70 | CYP19A1 (0.48) | PPIAPPIFCYP19A1KMT2AMEN1 | |
| SCHEMBL5036374 | 0.70 | MGMT (0.58) | CYP19A1KMT2AMEN1MAPTCYP11B1 | |
| SCHEMBL18396641 | 0.70 | PIN1 (0.51) | PPIAPPIFCYP19A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |