Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 10/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13424801 | 0.88 | NPC1 (0.43) | MAPT | |
| SCHEMBL3352616 | 0.85 | PPIA (0.47) | PPIALTA4HMAPK14BRD4 | |
| SCHEMBL3345757 | 0.83 | PPIA (0.44) | PPIAMAPT | |
| SCHEMBL13424802 | 0.75 | KDM4E (0.40) | MAPT | |
| SCHEMBL8520827 | 0.75 | PPIA (0.43) | PPIALTA4HBRD4 | |
| SCHEMBL15156727 | 0.74 | KDM4E (0.42) | MAPT | |
| SCHEMBL646567 | 0.72 | BRD4 (0.42) | BRD4TDP1 | |
| SCHEMBL28302706 | 0.70 | PDK1 (0.57) | LTA4HMAPT | |
| SCHEMBL3916435 | 0.70 | LTA4H (0.39) | LTA4HBRD4MAPTTDP1 | |
| SCHEMBL21439550 | 0.69 | PPIA (0.47) | PPIALTA4HMAPK14BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |