Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 8/20 | 0.49 |
| ▸ | PPIF | P30405 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MGMT | P16455 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345757 | 0.86 | PPIA (0.44) | PPIAPPIFCYP19A1KMT2AMEN1 | |
| SCHEMBL3352616 | 0.80 | PPIA (0.47) | PPIA | |
| SCHEMBL18396641 | 0.76 | PIN1 (0.51) | PPIAPPIFCYP19A1KMT2AMEN1 | |
| SCHEMBL3345345 | 0.76 | CYP19A1 (0.48) | PPIAPPIFCYP19A1KMT2AMEN1 | |
| SCHEMBL5036374 | 0.76 | MGMT (0.58) | CYP19A1KMT2AMEN1HTTMGMT | |
| SCHEMBL13424800 | 0.75 | NPC1 (0.42) | PPIAPPIFCYP19A1KMT2AHTT | |
| SCHEMBL5033956 | 0.73 | HTT (0.52) | HTTMAPT | |
| SCHEMBL15013285 | 0.73 | MAPT (0.55) | PPIACYP19A1KMT2AMEN1MGMT | |
| SCHEMBL18396644 | 0.73 | KMT2A (0.50) | PPIAPPIFCYP19A1KMT2AMEN1 | |
| SCHEMBL2986814 | 0.71 | HPD (0.57) | PPIAKMT2AMEN1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |