Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345924 | 1.00 | MGLL (0.41) | MGLLFFAR4MDM2TP53OGA | |
| SCHEMBL2425356 | 0.84 | MGLL (0.44) | MGLLFFAR4 | |
| SCHEMBL3346464 | 0.79 | MGLL (0.45) | MGLLFFAR4TP53NPC1 | |
| SCHEMBL3346469 | 0.79 | MGLL (0.45) | MGLLFFAR4TP53NPC1 | |
| SCHEMBL2424213 | 0.78 | CACNA1H (0.36) | MGLLOGACACNA1H | |
| SCHEMBL18446074 | 0.77 | MGLL (0.50) | MGLL | |
| Hydrochloric Acid SCHEMBL2423115 | 0.77 | TRPM5 (0.34) | — | |
| SCHEMBL2420942 | 0.76 | MGLL (0.48) | MGLLFFAR4 | |
| SCHEMBL3346282 | 0.75 | MGLL (0.51) | MGLLFFAR4OGA | |
| SCHEMBL3350922 | 0.75 | MGLL (0.51) | MGLLFFAR4OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058318-A1 | 1-OXA-8-AZASPIRO [4, 5 ] DECANE- 8 -CARBOXAMIDE COMPOUNDS AS FAAH INHIBITORS | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |