Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 17/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347660 | 0.87 | KDM4E (0.31) | GRM5 | |
| SCHEMBL3352981 | 0.83 | GRM5 (0.41) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL3346856 | 0.81 | GRM5 (0.52) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL3351704 | 0.81 | KDM4E (0.34) | GRM5 | |
| SCHEMBL3347055 | 0.80 | GRM5 (0.51) | GRM5CYP1A2 | |
| SCHEMBL3345855 | 0.80 | KDM4E (0.33) | CYP1A2CYP2D6 | |
| SCHEMBL3347231 | 0.80 | GRM5 (0.35) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL3347664 | 0.80 | GRM5 (0.37) | GRM5 | |
| SCHEMBL3345928 | 0.79 | GRM5 (0.36) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL3347064 | 0.79 | GRM5 (0.39) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |