Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 13/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352619 | 0.85 | PPIA (0.41) | PPIALTA4HMAPK14BRD4 | |
| SCHEMBL3345989 | 0.80 | PPIA (0.49) | PPIA | |
| SCHEMBL5033887 | 0.74 | LTA4H (0.67) | LTA4HMAPK14 | |
| SCHEMBL5843850 | 0.73 | BRD4 (0.63) | PPIAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL1669341 | 0.69 | SHMT2 (0.45) | — | |
| SCHEMBL27647891 | 0.69 | F2 (0.46) | PPIASGMS2 | |
| SCHEMBL10424550 | 0.69 | PPIA (0.74) | PPIA | |
| SCHEMBL8566190 | 0.69 | KMT2A (0.58) | PPIALTA4HMAPK14SGMS2 | |
| SCHEMBL11094009 | 0.68 | PTGER1 (0.61) | LTA4HMAPK14PTGER1PTGER4PTGER3 | |
| SCHEMBL10819322 | 0.68 | MAPT (0.56) | PPIALTA4HMAPK14BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |