Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | CDC42 | P60953 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22179085 | 0.84 | MC4R (0.58) | CNR1MC4RKDM4EHSD17B10 | |
| SCHEMBL3346376 | 0.84 | MC4R (0.63) | CNR1MC4RKCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL22160560 | 0.83 | MC4R (0.57) | CNR1MC4RKDM4EHSD17B10 | |
| SCHEMBL3347924 | 0.82 | TAAR1 (0.52) | CNR1MC4RKCNH2ROCK2HSD17B10 | |
| SCHEMBL3380087 | 0.81 | MC4R (0.66) | MC4R | |
| SCHEMBL3345900 | 0.81 | KCNH2 (0.58) | MC4RKCNH2KDM4EHSD17B10 | |
| SCHEMBL3353041 | 0.81 | CNR1 (0.55) | CNR1MC4RKCNH2ROCK2CDC42 | |
| SCHEMBL3348201 | 0.79 | CNR1 (0.54) | CNR1MC4RROCK2KDM4E | |
| Hydrochloric Acid SCHEMBL28625482 | 0.78 | MC4R (0.51) | CNR1MC4RKDM4EHSD17B10 | |
| SCHEMBL3350700 | 0.76 | ROCK2 (0.42) | MC4RKCNH2ROCK2CDC42PRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |