Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | FPR3 | P25089 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346450 | 0.86 | FPR3 (0.48) | CNR1FPR3SMN1; SMN2POLBALOX5AP | |
| SCHEMBL3347825 | 0.83 | GPBAR1 (0.43) | MC4RGPBAR1ROCK2 | |
| SCHEMBL3346376 | 0.83 | MC4R (0.63) | CNR1SMN1; SMN2POLBALDH1A1MC4R | |
| SCHEMBL3346908 | 0.80 | MAPT (0.48) | SMN1; SMN2POLBALDH1A1KDM4EMC4R | |
| SCHEMBL3346412 | 0.79 | CNR1 (0.53) | CNR1KDM4EMC4RROCK2 | |
| SCHEMBL3347924 | 0.76 | TAAR1 (0.52) | CNR1POLBALDH1A1MC4RMAPT | |
| Hydrochloric Acid SCHEMBL21640657 | 0.76 | HSD11B1 (0.54) | CNR1FPR3SMN1; SMN2POLBALOX5AP | |
| Hydrochloric Acid SCHEMBL30585928 | 0.76 | HSD11B1 (0.54) | CNR1FPR3SMN1; SMN2POLBALOX5AP | |
| SCHEMBL3380087 | 0.76 | MC4R (0.66) | POLBALDH1A1MC4RPKMRAB9A | |
| SCHEMBL3346461 | 0.76 | KCNH2 (0.46) | FPR3SMN1; SMN2ALOX5APALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |