Sugi Predict

Sugi Predict / Compounds / SCHEMBL3346429

SCHEMBL3346429

SCHEMBL3346429

c1ccc(OC(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 3/20 0.50
▸ TSHR P16473 1/20 0.50
▸ CA4 P22748 1/20 0.45
▸ CYP1A2 P05177 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ KCNA3 P22001 1/20 0.41
▸ CA5A P35218 1/20 0.39
▸ CA5B Q9Y2D0 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ SLC6A4 P31645 1/20 0.39
▸ HPGD P15428 1/20 0.38
▸ MTNR1A P48039 1/20 0.38
▸ MTNR1B P49286 1/20 0.38
▸ NR1H2 P55055 1/20 0.38
▸ BAX Q07812 1/20 0.38
▸ MAOA P21397 1/20 0.38
▸ LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9770363 0.88 LTA4H (0.45) LTA4HTSHRCA4CYP1A2GAA
SCHEMBL11577579 0.84 PPARG (0.51) TSHRSLC6A4
SCHEMBL28445107 0.83 LTA4H (0.41) LTA4HTSHRCA4CYP1A2GAA
SCHEMBL3906412 0.83 CA4 (0.50) LTA4HTSHRCA4CYP1A2GAA
SCHEMBL11340031 0.81 LTA4H (0.39) LTA4HTSHRCA4KCNA3KDM4E
SCHEMBL11579861 0.81 KCNA3 (0.44) LTA4HTSHRCA4GAAKCNA3
SCHEMBL11581977 0.81 PPARG (0.50) CYP1A2GAAKDM4ESLC6A4LMNA
SCHEMBL29039045 0.81 CA4 (0.42) LTA4HTSHRCA4CYP1A2GAA
SCHEMBL11580062 0.79 MAPT (0.49) TSHRCYP1A2GAACYP2C9PKM
SCHEMBL10949753 0.79 SMN1; SMN2 (0.47) TSHRCYP1A2GAACYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115108965-A Preparation method of anti-neocoronarism drug Parovidekey intermediate 上海再启生物技术有限公司 2022-09-27 — — CN claimed
CN-111018825-B Synthetic method of 2-bromo-3, 4-methylenedioxy-5-methoxybenzoic acid methyl ester 苏州诚和医药化学有限公司 2020-12-22 — — CN claimed
CN-111018825-A Synthetic method of 2-bromo-3, 4-methylenedioxy-5-methoxybenzoic acid methyl ester 苏州诚和医药化学有限公司 2020-04-17 — — CN claimed
WO-1994001394-A1 PREPARATION OF N-ARYL AMIDES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1994-01-20 — — WO claimed
CN-117069771-A Metallocene-non-metallocene complex, preparation method thereof and application thereof in preparation of disentangled ultra-high molecular weight polyethylene 中国科学院长春应用化学研究所 2023-11-17 — — CN disclosed
US-20230322742-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES AGILENT TECHNOLOGIES, INC. 2023-10-12 — — US disclosed
CN-115108965-B Preparation method of key intermediate of anti-new crown drug Pa Luo Weide 上海再启生物技术有限公司 2023-08-25 — — CN disclosed
CN-115108965-A Preparation method of anti-neocoronarism drug Parovidekey intermediate 上海再启生物技术有限公司 2022-09-27 — — CN disclosed
US-11261153-B2 Organic amine salt compounds having CO2-donating anions and their use as foaming agent SHANDONG UNIVERSITY OF TECHNOLOGY (CN) 2022-03-01 — — US disclosed
US-20220035216-A1 ELECTROCHROMIC ELEMENT, AND METHOD FOR DRIVING THE SAME RICOH COMPANY, LTD. (JP) 2022-02-03 — — US disclosed
US-11236050-B2 Polymorphs of 4-[3-chloro-4-(n′-cyclopropyl ureido)phenoxy] -7-methoxyquinoline-6-carboxamide, its salts and process for the preparation thereof MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2022-02-01 — — US disclosed
EP-3466916-B1 ORGANIC AMINE SALT COMPOUND HAVING ANIONS SERVING AS CO2 DONORS AND APPLICATION OF SAME AS FOAMING AGENT UNIV SHANDONG TECHNOLOGY (CN) 2021-09-29 — — EP disclosed
US-4136252-A POLYETHERS, SUSTAINED RELEASE COATINGS ALZA CORPORATION (US) 1979-01-23 — — US disclosed
US-4119579-A Polymeric orthoesters ALZA CORPORATION (US) 1978-10-10 — — US disclosed
US-4066747-A Polymeric orthoesters housing beneficial drug for controlled release therefrom ALZA CORPORATION (US) 1978-01-03 — — US disclosed
US-3992436-A Synthesis of oxalate esters from carbon monoxide and carboxylic ortho esters ATLANTIC RICHFIELD COMPANY (US) 1976-11-16 — — US disclosed
US-3962318-A Substituted ethane diphosphonic acids and salts and esters thereof MONSANTO COMPANY (US) 1976-06-08 — — US disclosed
US-3957858-A SUBSTITUTED ETHANE DIPHOSPHONIC ACIDS AND SALTS AND ESTERS THEREOF MONSANTO COMPANY (US) 1976-05-18 — — US disclosed
US-3944599-A Substituted ethane diphosphonic acids and salts MONSANTO COMPANY (US) 1976-03-16 — — US disclosed
US-3940436-A Substituted ethane diphosphonic acids and salts and esters thereof MONSANTO COMPANY (US) 1976-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11261153-B2 Organic amine salt compounds having CO2-donating anions and their use as foaming agent PHOSPHO1, METTL14, ALKBH3 LTA4H 2694/4885TSHR 4164/4885CA4 188/4885
US-11236050-B2 Polymorphs of 4-[3-chloro-4-(n′-cyclopropyl ureido)phenoxy] -7-methoxyquinoline-6-carboxamide, its salts and process for the preparation thereof UGT1A1, CYP4B1, CYP1B1 LTA4H 3015/4885TSHR 4413/4885CA4 1023/4885
US-20230322742-A1 ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES RNGTT, OSBPL8, DCLRE1B LTA4H 3843/4885TSHR 428/4885CA4 3077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.