Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 2/20 | 0.48 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346278 | 0.87 | CNR1 (0.57) | KCNH2MC4RCA1CA2MTNR1A | |
| SCHEMBL3348187 | 0.87 | KCNH2 (0.48) | KCNH2MC4RRAB9ACA1CA2 | |
| SCHEMBL3346356 | 0.85 | KCNH2 (0.57) | KCNH2KDM4EMEN1KMT2AMC4R | |
| SCHEMBL3346236 | 0.85 | MC4R (0.65) | KCNH2MC4R | |
| SCHEMBL3353235 | 0.84 | ROCK2 (0.49) | KCNH2KDM4EMC4RRAB9ACA1 | |
| SCHEMBL3347960 | 0.83 | CNR1 (0.52) | MEN1KMT2AMC4RRAB9ACA1 | |
| SCHEMBL3352433 | 0.81 | CNR1 (0.46) | KCNH2MEN1KMT2AMC4RRAB9A | |
| SCHEMBL3346031 | 0.80 | KCNH2 (0.53) | KCNH2MC4RDGAT2 | |
| SCHEMBL3346490 | 0.79 | KCNH2 (0.65) | KCNH2MEN1KMT2ADGAT2 | |
| SCHEMBL21994259 | 0.79 | KCNH2 (0.63) | KCNH2KDM4EMEN1KMT2ADGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | disclosed |