Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346278 | 0.90 | CNR1 (0.57) | ROCK2CA1CA2CNR1ALDH1A1 | |
| SCHEMBL3347960 | 0.88 | CNR1 (0.52) | ROCK2CA1CA2CNR1ALDH1A1 | |
| SCHEMBL3348187 | 0.86 | KCNH2 (0.48) | CA1CA2CNR1ALDH1A1KCNH2 | |
| SCHEMBL3352433 | 0.86 | CNR1 (0.46) | ROCK2CA1CA2CNR1KCNH2 | |
| SCHEMBL3353044 | 0.85 | KCNH2 (0.46) | ROCK2CNR1ALDH1A1KCNH2MC4R | |
| SCHEMBL3346496 | 0.84 | KCNH2 (0.56) | CA1CA2CNR1KDM4EKCNH2 | |
| SCHEMBL3350733 | 0.83 | CNR1 (0.48) | CA1CA2CNR1ALDH1A1MTNR1A | |
| SCHEMBL3350728 | 0.82 | CNR1 (0.47) | ROCK2CA1CA2CNR1ALDH1A1 | |
| SCHEMBL3346695 | 0.80 | CNR1 (0.50) | ROCK2CA1CA2CNR1ALDH1A1 | |
| SCHEMBL13365092 | 0.80 | KCNH2 (0.54) | ROCK2ALDH1A1KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | disclosed |