Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | GPR39 | O43194 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3410485 | 0.88 | MC4R (0.43) | CNR1ROCK2MC4RKCNH2RAB9A | |
| SCHEMBL3348171 | 0.88 | TAAR1 (0.53) | CNR1MEN1KMT2AMC4RKCNH2 | |
| SCHEMBL3346278 | 0.88 | CNR1 (0.57) | CNR1ROCK2CA1CA2MC4R | |
| SCHEMBL3353235 | 0.86 | ROCK2 (0.49) | CNR1ROCK2CA1CA2GPR39 | |
| SCHEMBL3353112 | 0.86 | MC4R (0.43) | CNR1ROCK2MC4RKCNH2RAB9A | |
| SCHEMBL3347960 | 0.86 | CNR1 (0.52) | CNR1ROCK2MEN1KMT2ACA1 | |
| SCHEMBL3410126 | 0.85 | MC4R (0.57) | MC4RKCNH2RAB9A | |
| SCHEMBL3348187 | 0.84 | KCNH2 (0.48) | CNR1CA1CA2MC4RMTNR1A | |
| SCHEMBL3346695 | 0.84 | CNR1 (0.50) | CNR1ROCK2CA1CA2ROCK1 | |
| SCHEMBL3346496 | 0.81 | KCNH2 (0.56) | CNR1MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |