Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.50 |
| ▸ | F10 | P00742 | 4/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45875 | 0.82 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1HSD17B1BACE1ESR1 | |
| SCHEMBL17826838 | 0.79 | PRSS1 (0.46) | PRSS1PRSS2PRSS3PLGF2 | |
| SCHEMBL18720225 | 0.78 | F10 (0.48) | PRSS1F10PRSS2PRSS3F12 | |
| SCHEMBL5845887 | 0.78 | PRSS1 (0.44) | PRSS1F10PRSS2PRSS3F12 | |
| SCHEMBL9763047 | 0.78 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1HSD17B1BACE1ESR1 | |
| SCHEMBL385574 | 0.76 | PKM (0.75) | HSP90AA1HSP90AB1HSD17B1BACE1ESR1 | |
| SCHEMBL487507 | 0.76 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1HSD17B1BACE1ESR1 | |
| SCHEMBL18977485 | 0.76 | PRSS1 (0.46) | PRSS1PRSS2PRSS3PLGF2 | |
| Hydrochloric Acid SCHEMBL6726373 | 0.75 | PRSS1 (0.43) | PRSS1F10PRSS2PRSS3ALDH1A1 | |
| SCHEMBL9314470 | 0.74 | LMNA (0.54) | PRSS1PRSS2PRSS3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |