Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.65 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654136 | 0.86 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1HSD17B1PKMSLC22A6 | |
| SCHEMBL385574 | 0.85 | PKM (0.75) | HSP90AA1HSP90AB1HSD17B1PKMESR1 | |
| SCHEMBL487507 | 0.85 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1HSD17B1PKMESR1 | |
| SCHEMBL2856590 | 0.83 | HTT (0.68) | HSP90AA1HSP90AB1HSD17B1PKMESR1 | |
| SCHEMBL45875 | 0.83 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1HSD17B1PKMESR1 | |
| SCHEMBL10914230 | 0.82 | SMN1; SMN2 (0.44) | HSP90AA1HSP90AB1HSD17B1PKMESR1 | |
| SCHEMBL6756073 | 0.82 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1HSD17B1PKMESR1 | |
| SCHEMBL10911335 | 0.82 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1HSD17B1PKMESR1 | |
| SCHEMBL27405963 | 0.81 | PKM (0.48) | HSP90AA1HSP90AB1HSD17B1PKMESR1 | |
| SCHEMBL8772648 | 0.80 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1HSD17B1PKMESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021528-A | Crosslinked bisphenol containing arylcyclobutene alkyl ethers and cured compositions therefrom | SHELL OIL COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| US-4994548-A | Modified bisphenol resins having at least one arylcyclo-butanenealkyl moiety | SHELL OIL COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0397277-A2 | Modified bisphenols | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-11-14 | — | — | EP | disclosed |
| US-4960956-A | Modified bisphenols having at least one arylcyclobutenealkyl moiety and cured products therefrom | SHELL OIL COMPANY (US) | 1990-10-02 | — | — | US | disclosed |
| US-4943665-A | Modified bisphenols containing arylcyclobutenealkyl ethers and cured compositions therefrom | SHELL OIL COMPANY (US) | 1990-07-24 | — | — | US | disclosed |