SCHEMBL33473

SCHEMBL33473

C=CC(=O)OCCC(=O)Cl

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.58
ALDH1A1 P00352 5/20 0.58
TP53 P04637 4/20 0.58
HIF1A Q16665 3/20 0.58
CYP3A4 P08684 2/20 0.58
HSD17B10 Q99714 1/20 0.58
HPGD P15428 1/20 0.52
THRB P10828 2/20 0.43
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13139413 0.87 TSHR (0.65) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11029337 0.84 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL33482 0.84 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL731717 0.84 TSHR (0.73) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10917679 0.81 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15435511 0.80 TSHR (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL93462 0.80 TSHR (0.84) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30604742 0.80 TSHR (0.84) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL12547083 0.79 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL4343485 0.79 TSHR (0.67) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12098223-B2 Living radical polymerization method using zinc phthalocyanine dye as near-infrared photocatalyst SOOCHOW UNIVERSITY (CN) 2024-09-24 US disclosed
US-20230027085-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED PRODUCT OF FLUORORESIN, FLUORORESIN, FLUORORESIN FILM, BANK AND DISPLAY ELEMENT CENTRAL GLASS COMPANY, LIMITED (JP) 2023-01-26 US disclosed
US-20220325008-A1 LIVING RADICAL POLYMERIZATION METHOD USING ZINC PHTHALOCYANINE DYE AS NEAR-INFRARED PHOTOCATALYST SOOCHOW UNIVERSITY (CN) 2022-10-13 US disclosed
WO-2022021499-A1 ACTIVE FREE RADICAL POLYMERIZATION METHOD WITH ZINC PHTHALOCYANINE DYE AS NEAR-INFRARED LIGHT CATALYST 苏州大学 2022-02-03 WO disclosed
WO-2022021499-A1 ACTIVE FREE RADICAL POLYMERIZATION METHOD WITH ZINC PHTHALOCYANINE DYE AS NEAR-INFRARED LIGHT CATALYST 苏州大学 2022-02-03 WO disclosed
CN-111875736-B Active free radical polymerization method using phthalocyanine zinc dye as near infrared light catalyst 苏州大学 2021-05-04 CN disclosed
CN-111875736-A Active free radical polymerization method using phthalocyanine zinc dye as near infrared light catalyst 苏州大学 2020-11-03 CN disclosed
WO-2020110793-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING CURED PRODUCT OF FLUORORESIN, FLUORORESIN, FLUORORESIN FILM, BANK AND DISPLAY ELEMENT セントラル硝子株式会社 2020-06-04 WO disclosed
US-8999377-B2 System for forming a biocompatible foam using polymerizable alpha(1-4)glucopyranose polymers and gas-producing component SURMODICS, INC. (US) 2015-04-07 US disclosed
EP-2084196-B1 SHAPE MEMORY POLYMERS UNIV ROCHESTER (US) 2014-01-22 EP disclosed
US-20070065482-A1 Articles including natural biodegradable polysaccharides and uses thereof SURMODICS MD, LLC 2007-03-22 US disclosed
US-20070065482-A1 Articles including natural biodegradable polysaccharides and uses thereof SURMODICS MD, LLC 2007-03-22 US disclosed
US-20070065482-A1 Articles including natural biodegradable polysaccharides and uses thereof SURMODICS MD, LLC 2007-03-22 US disclosed
US-20070065483-A1 In vivo formed matrices including natural biodegradable polysaccharides and uses thereof SURMODICS MD, LLC 2007-03-22 US disclosed
US-20070065483-A1 In vivo formed matrices including natural biodegradable polysaccharides and uses thereof SURMODICS MD, LLC 2007-03-22 US disclosed
US-20070065483-A1 In vivo formed matrices including natural biodegradable polysaccharides and uses thereof SURMODICS MD, LLC 2007-03-22 US disclosed
US-20070065484-A1 In situ occlusion using natural biodegradable polysaccharides SURMODICS MD, LLC 2007-03-22 US disclosed
EP-1755696-A1 NATURAL BIODEGRADABLE POLYSACCHARIDE COATINGS FOR MEDICAL ARTICLES SurModics, Inc. (US) 2007-02-28 EP disclosed
WO-2005113034-A1 NATURAL BIODEGRADABLE POLYSACCHARIDES COATINGS FOR MEDICAL ARTICLES SURMODICS, INC. (US) 2005-12-01 WO disclosed
US-20050255142-A1 Coatings for medical articles including natural biodegradable polysaccharides SURMODICS, INC. 2005-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070065482-A1 Articles including natural biodegradable polysaccharides and uses thereof CD44, FUT6, FGF23 TSHR 2597/4885ALDH1A1 1429/4885TP53 2988/4885
US-20070065483-A1 In vivo formed matrices including natural biodegradable polysaccharides and uses thereof CD44, ADAMTS4, BMP2 TSHR 3925/4885ALDH1A1 1574/4885TP53 2036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.