Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13697336 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HPGDHSP90AA1METAP2GAA | |
| SCHEMBL25390259 | 0.83 | HSP90AA1 (0.43) | ALDH1A1HSP90AA1MAPTHSP90AB1ERN1 | |
| SCHEMBL30570371 | 0.83 | HSP90AA1 (0.43) | ALDH1A1HSP90AA1MAPTHSP90AB1ERN1 | |
| SCHEMBL3629826 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDHSP90AA1METAP2GAA | |
| SCHEMBL4213590 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSP90AA1METAP2GAA | |
| SCHEMBL2542645 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSP90AA1METAP2GAA | |
| SCHEMBL6621471 | 0.79 | ACACA (0.47) | ALDH1A1HPGDHSD17B10MAPTERN1 | |
| SCHEMBL10751660 | 0.78 | IDO1 (0.40) | ALDH1A1HPGDMETAP2GAAHSD17B10 | |
| SCHEMBL10372922 | 0.76 | HSP90AA1 (0.57) | ALDH1A1HPGDHSP90AA1METAP2GAA | |
| SCHEMBL12445676 | 0.76 | MEN1 (0.43) | ALDH1A1HPGDERN1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143216-A | Antibacterial biaromatic derivatives | ACTELION PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | disclosed |
| EP-2010550-B1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL RES & TECHNOLOGY FELUY (BE) | 2013-06-19 | — | — | EP | disclosed |
| EP-2010550-B1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL RES & TECHNOLOGY FELUY (BE) | 2013-06-19 | — | — | EP | disclosed |
| US-8399582-B2 | Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-03-19 | — | — | US | disclosed |
| US-8399582-B2 | Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-03-19 | — | — | US | disclosed |
| US-8399582-B2 | Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2013-03-19 | — | — | US | disclosed |
| US-20100160583-A1 | Polymerisation of Ethylene and Alpha-Olefins with Pyridino-Iminophenol Complexes | TOTAL PETROCHEMICALS RESEARCH FEULY (BE) | 2010-06-24 | — | — | US | disclosed |
| US-20100160583-A1 | Polymerisation of Ethylene and Alpha-Olefins with Pyridino-Iminophenol Complexes | TOTAL PETROCHEMICALS RESEARCH FEULY (BE) | 2010-06-24 | — | — | US | disclosed |
| US-20100160583-A1 | Polymerisation of Ethylene and Alpha-Olefins with Pyridino-Iminophenol Complexes | TOTAL PETROCHEMICALS RESEARCH FEULY (BE) | 2010-06-24 | — | — | US | disclosed |
| WO-2007122139-A1 | POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-11-01 | — | — | WO | disclosed |