Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CBFB | Q13951 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347478 | 0.83 | ALDH1A1 (0.47) | ALDH1A1ERN1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL25390259 | 0.74 | HSP90AA1 (0.43) | ALDH1A1ERN1NFE2L2SMN1; SMN2HSP90AA1 | |
| SCHEMBL30570371 | 0.74 | HSP90AA1 (0.43) | ALDH1A1ERN1NFE2L2SMN1; SMN2HSP90AA1 | |
| SCHEMBL4159378 | 0.74 | CYP1A2 (0.50) | ALDH1A1PTGER1CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL6621471 | 0.70 | ACACA (0.47) | ALDH1A1ERN1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL5620804 | 0.68 | CYP2C9 (0.51) | ALDH1A1PTGER1CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL15332409 | 0.67 | DCUN1D1 (0.48) | ALDH1A1ERN1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL25392126 | 0.67 | TERT (0.44) | ALDH1A1ERN1CYP3A4HSP90AA1GAA | |
| SCHEMBL31505930 | 0.67 | CYP1A2 (0.58) | ALDH1A1CYP3A4CYP2C19CYP2C9KDM4E | |
| SCHEMBL30137531 | 0.67 | ALDH1A1 (0.52) | ALDH1A1ERN1HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | GLAXO GROUP LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227591-A1 | Cyclopentene compounds | C1R, CYP1B1, ADORA2B | ALDH1A1 1534/4885ERN1 1619/4885PTGER1 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.