Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 10/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700281 | 0.81 | KDM4E (0.47) | CYP2A6CYP3A4ALDH1A1KDM4EMAPT | |
| SCHEMBL7092910 | 0.81 | CYP2A6 (0.67) | CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL19961426 | 0.79 | CYP11B1 (0.44) | CYP2A6KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL29249875 | 0.78 | HDAC8 (0.45) | CYP2A6CYP3A4ALDH1A1KDM4ELMNA | |
| SCHEMBL31092839 | 0.78 | HDAC8 (0.45) | CYP2A6CYP3A4ALDH1A1KDM4ELMNA | |
| SCHEMBL28181896 | 0.78 | PTGS2 (0.64) | CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL30032 | 0.78 | PTGS2 (0.64) | CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL31635952 | 0.78 | PTGS2 (0.64) | CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL10035263 | 0.76 | CYP2A6 (0.61) | CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL1777671 | 0.76 | PTGS2 (0.62) | CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10461263-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-10-29 | — | — | US | disclosed |
| US-20180076396-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-03-15 | — | — | US | disclosed |
| US-8097594-B2 | Macrolides and ketolides having antimicrobial activity | WOCKHARDT LTD. (IN) | 2012-01-17 | — | — | US | disclosed |
| US-20090247478-A1 | Novel macrolides and ketolides having antimicrobial activity | SINDKHEDKAR MILIND DATTATRAYA | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247478-A1 | Novel macrolides and ketolides having antimicrobial activity | CYP51A1, CASP12, LSS | CYP2A6 814/4885CYP3A4 422/4885ALDH1A1 4164/4885 |
| US-10461263-B2 | Condensed cyclic compound and organic light-emitting device including the same | CRY1, CCNA1, CCNE2 | CYP2A6 2399/4885CYP3A4 1644/4885ALDH1A1 246/4885 |
| US-20180076396-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CCNA1, CCNE2 | CYP2A6 2399/4885CYP3A4 1644/4885ALDH1A1 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.