Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | PRF1 | P14222 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3620203 | 0.89 | TLR8 (0.44) | KMT2AGSK3BPDE4APDE4BPDE4C | |
| SCHEMBL27961477 | 0.86 | KMT2A (0.51) | KMT2AGSK3BPDE4APDE4BPDE4C | |
| SCHEMBL4768283 | 0.85 | KMT2A (0.57) | KMT2AGSK3BPDE4APDE4BPDE4C | |
| SCHEMBL3626765 | 0.79 | GSK3B (0.48) | KMT2AGSK3BPDE4APDE4BPDE4C | |
| SCHEMBL8258906 | 0.79 | MAPK1 (0.54) | GSK3BABCB1ABCC1 | |
| SCHEMBL319254 | 0.77 | KMT2A (0.58) | KMT2AGSK3BGRM2 | |
| SCHEMBL30074643 | 0.77 | KMT2A (0.58) | KMT2AGSK3BGRM2 | |
| SCHEMBL28777569 | 0.77 | GRM5 (0.50) | GSK3BHPGDSMAP4K4MKNK1MKNK2 | |
| SCHEMBL945743 | 0.77 | GSK3B (0.63) | KMT2AGSK3BPDE4APDE4BPDE4C | |
| SCHEMBL3625940 | 0.77 | HPGDS (0.44) | GSK3BHPGDSMAP4K4CHEK2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408767-B1 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2013-07-10 | — | — | EP | claimed |
| CN-102356079-A | Amide derivatives as neuropeptide y5 receptor ligands | LUNDBECK & CO AS H | 2012-02-15 | — | — | CN | claimed |
| WO-2010108052-A2 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2010-09-23 | — | — | WO | claimed |
| EP-2408767-B1 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2013-07-10 | — | — | EP | disclosed |
| CN-102356079-A | Amide derivatives as neuropeptide y5 receptor ligands | LUNDBECK & CO AS H | 2012-02-15 | — | — | CN | disclosed |
| WO-2010108052-A2 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |