Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 20/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 20/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13074172 | 0.92 | ADRA1D (0.60) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL6468404 | 0.92 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL18306489 | 0.91 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL13037437 | 0.90 | ADRA1D (0.65) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL13730436 | 0.90 | ADRA1D (0.75) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL526322 | 0.90 | ADRA1D (0.75) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL13731163 | 0.89 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL13736802 | 0.89 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL13415877 | 0.89 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL12657993 | 0.89 | ADRA1D (0.63) | ADRA1DADRA1AADRA1BADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118606-A2 | A NOVEL PROCESS FOR THE PREPARATION OF SILODOSIN | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2014-08-07 | — | — | WO | claimed |
| US-9745264-B2 | Method for preparing silodosin and intermediate thereof | SHANGHAI SYNCORES TECHNOLOGIES, INC. (CN) | 2017-08-29 | — | — | US | disclosed |
| WO-2014118606-A2 | A NOVEL PROCESS FOR THE PREPARATION OF SILODOSIN | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014118606-A2 | A NOVEL PROCESS FOR THE PREPARATION OF SILODOSIN | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2014-08-07 | — | — | WO | disclosed |
| EP-2172443-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE | HAMARI CHEMICALS LTD (JP) | 2013-03-27 | — | — | EP | disclosed |
| US-8222452-B2 | Method for producing optically active amines | HAMARI CHEMICALS, LTD. (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100160636-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | HAMARI CHEMICALS, LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2172443-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINE | Hamari Chemicals, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160636-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | INMT, HNMT, PADI3 | ADRA1D 1633/4885ADRA1A 1737/4885ADRA1B 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.