Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL105262 | 0.85 | IRAK4 (0.55) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL31632660 | 0.85 | IRAK4 (0.55) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL28294057 | 0.83 | IRAK4 (0.53) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9783644 | 0.83 | IRAK4 (0.53) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL7849679 | 0.83 | IRAK4 (0.53) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL5134567 | 0.83 | KDM4E (0.50) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL305563 | 0.82 | IRAK4 (0.52) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL31400625 | 0.82 | IRAK4 (0.52) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL731619 | 0.82 | IRAK4 (0.52) | IRAK4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10407367 | 0.80 | IRAK4 (0.50) | IRAK4KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391594-A1 | RADIOFLUORINATION | Hammersmith Imanet Limited (GB) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010060694-A1 | RADIOFLUORINATION | HAMMERSMITH IMANET LIMITED (GB) | 2010-06-03 | — | — | WO | disclosed |