Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24828 | 0.79 | TRPA1 (0.54) | TRPA1BACE1L3MBTL1BCHEMEN1 | |
| SCHEMBL2511192 | 0.71 | TRPA1 (0.42) | TRPA1BACE1ALDH1A1BCHEMEN1 | |
| SCHEMBL8834254 | 0.71 | TRPA1 (0.42) | TRPA1BACE1BCHEMEN1CYP1A2 | |
| SCHEMBL9599363 | 0.70 | VHL (0.37) | L3MBTL1HPGDBCHEMEN1POLB | |
| SCHEMBL10651476 | 0.67 | TRPA1 (0.38) | TRPA1BACE1MAOA | |
| SCHEMBL5388076 | 0.67 | OPRK1 (0.36) | TRPA1ALDH1A1HPGDMEN1POLB | |
| SCHEMBL5376724 | 0.67 | TRPA1 (0.38) | TRPA1BACE1KDM4EALDH1A1HPGD | |
| Thianthrene SCHEMBL7786 | 0.66 | BCHE (0.56) | TRPA1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL21629348 | 0.66 | BCHE (0.56) | TRPA1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL30823 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 979 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024035950-A1 | INHIBITORS OF KIF18A AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2024-02-15 | — | — | WO | claimed |
| CN-116693502-A | Heterocyclic amine menin-MLL interaction inhibitor, preparation method and application thereof | 成都硕德药业有限公司 | 2023-09-05 | — | — | CN | claimed |
| EP-3632443-B1 | ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-06-07 | — | — | EP | claimed |
| EP-3381896-B1 | BIPHENYL COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-01-18 | — | — | EP | claimed |
| CN-108602770-B | Novel biphenyl compound or salt thereof | 大鹏药品工业株式会社 | 2022-02-08 | — | — | CN | claimed |
| US-20210177826-A1 | ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-06-17 | — | — | US | claimed |
| US-10723742-B2 | Biphenyl compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-07-28 | — | — | US | claimed |
| US-20200190175-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2020-06-18 | — | — | US | claimed |
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | claimed |
| EP-3632443-A1 | ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | claimed |
| EP-1204323-A1 | FUNGICIDES | Aventis CropScience UK Limited (GB) | 2002-05-15 | — | — | EP | claimed |
| US-6369074-B1 | Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists | PFIZER INC. | 2002-04-09 | — | — | US | claimed |
| WO-2001011965-A1 | FUNGICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-22 | — | — | WO | claimed |
| WO-1997043282-A2 | BENZOTHIAZOLINONES AS ANTI-ASTHMATIC AGENTS | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | claimed |
| US-4591590-A | ANTIALLERGINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-27 | — | — | US | claimed |
| US-4581356-A | HYPOTENSIVE AND ANTIULCER AGENTS; ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-08 | — | — | US | claimed |
| US-4563455-A | Antiulcer fused imidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | claimed |
| EP-0125756-A2 | Fused imidazole compounds, processes for the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-21 | — | — | EP | claimed |
| EP-0122494-A2 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-24 | — | — | EP | claimed |
| EP-0113226-A1 | Benzhydrylpiperazine derivatives, processes for the preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210177826-A1 | ANTI-TUMOR EFFECT POTENTIATOR USING NOVEL BIPHENYL COMPOUND | KDM1B, KDM1A, DOT1L | TRPA1 3202/4885TYMS 4044/4885BACE1 1487/4885 |
| US-10723742-B2 | Biphenyl compound or salt thereof | KDM1B, BMI1, HDAC1 | TRPA1 1788/4885TYMS 4472/4885BACE1 1346/4885 |
| US-20200190175-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | INMT, CARM1, KDM1B | TRPA1 4871/4885TYMS 931/4885BACE1 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.