Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 14/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24188509 | 0.86 | SLC6A4 (0.40) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL3352752 | 0.86 | HTR1B (0.57) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL3352861 | 0.84 | DRD2 (0.55) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL17060397 | 0.83 | DRD2 (0.49) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL3351361 | 0.83 | DRD2 (0.50) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL17060402 | 0.82 | DRD2 (0.48) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL3355377 | 0.82 | DRD2 (0.62) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL3353028 | 0.80 | RORC (0.48) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL17495546 | 0.80 | RORC (0.50) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL26630179 | 0.78 | DRD2 (0.48) | DRD2SLC6A4HTR1DHTR1BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |