Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.62 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352752 | 0.86 | HTR1B (0.57) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL3352861 | 0.86 | DRD2 (0.55) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL17060397 | 0.83 | DRD2 (0.49) | DRD2SLC6A4HTR1DHTR1BMAPT | |
| SCHEMBL3351361 | 0.83 | DRD2 (0.50) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL17060402 | 0.82 | DRD2 (0.48) | DRD2SLC6A4HTR1DHTR1BMAPT | |
| SCHEMBL3348378 | 0.82 | DRD2 (0.49) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL17495546 | 0.80 | RORC (0.50) | DRD2SLC6A4HTR1DHTR1BRORC | |
| SCHEMBL3353028 | 0.80 | RORC (0.48) | DRD2SLC6A4HTR1DHTR1BKDM4E | |
| SCHEMBL26630179 | 0.78 | DRD2 (0.48) | DRD2SLC6A4HTR1DHTR1BKMT2A | |
| SCHEMBL3353204 | 0.76 | DRD2 (0.55) | DRD2SLC6A4HTR1DHTR1BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |