Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.65 |
| ▸ | NPC1 | O15118 | 10/20 | 0.65 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346059 | 0.86 | RAB9A (0.72) | RAB9ANPC1KDM5BHDAC2HDAC8 | |
| SCHEMBL7272416 | 0.83 | MGLL (0.74) | RAB9ANPC1KDM5BHDAC2HDAC8 | |
| SCHEMBL4747063 | 0.82 | KDM5B (0.56) | RAB9ANPC1KDM5BHDAC2HDAC8 | |
| SCHEMBL1925938 | 0.82 | L3MBTL1 (0.58) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20471980 | 0.81 | RAB9A (0.68) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4694649 | 0.80 | MCHR1 (0.55) | RAB9ANPC1KDM5BHDAC2HDAC8 | |
| SCHEMBL10160200 | 0.80 | KDM5B (0.69) | RAB9ANPC1KDM5BHDAC2HDAC8 | |
| SCHEMBL20472171 | 0.80 | AKR1C3 (0.67) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29818055 | 0.79 | RAB9A (1.00) | RAB9ANPC1KDM5BHDAC2HDAC8 | |
| SCHEMBL20804537 | 0.79 | SMN1; SMN2 (0.60) | RAB9ANPC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |