Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347609 | 0.77 | GRM5 (0.33) | GRM5 | |
| SCHEMBL3348444 | 0.67 | CHRM2 (0.35) | GRM5 | |
| SCHEMBL3347231 | 0.67 | GRM5 (0.35) | GRM5 | |
| SCHEMBL3348818 | 0.65 | GRM5 (0.47) | GRM5 | |
| SCHEMBL3347052 | 0.65 | CYP2A6 (0.37) | GRM5 | |
| SCHEMBL9903867 | 0.64 | KIT (0.42) | — | |
| SCHEMBL7567357 | 0.64 | GRM5 (0.42) | GRM5 | |
| SCHEMBL545332 | 0.62 | TGFBR1 (0.37) | — | |
| SCHEMBL28663062 | 0.62 | ADORA3 (0.45) | GRM5 | |
| SCHEMBL3347287 | 0.61 | DYRK1A (0.44) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | claimed |