Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 15/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346431 | 0.89 | PTPRC (0.36) | PTPRCPTPN2PTPN1PTPN6PTPN9 | |
| SCHEMBL3354223 | 0.80 | GRM5 (0.40) | GRM5HAO1 | |
| SCHEMBL3354005 | 0.79 | — | — | |
| SCHEMBL3347271 | 0.77 | DYRK1A (0.42) | IKBKBGRM5 | |
| SCHEMBL3351328 | 0.77 | CYP2A6 (0.34) | — | |
| SCHEMBL3345910 | 0.67 | GRM5 (0.35) | IKBKBGRM5 | |
| SCHEMBL25331092 | 0.66 | ALDH1A1 (0.44) | DHODH | |
| SCHEMBL9903113 | 0.66 | KIT (0.44) | GRM5 | |
| SCHEMBL3347239 | 0.65 | DYRK1A (0.45) | GRM5 | |
| SCHEMBL5263475 | 0.65 | SALL4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |