Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14246830 | 0.91 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTPDE3B | |
| SCHEMBL3349053 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTPDE3B | |
| SCHEMBL3345086 | 0.85 | ALKBH3 (0.42) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL3344710 | 0.81 | KDM4E (0.48) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL15931670 | 0.81 | KDM4E (0.47) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL3344690 | 0.80 | SMN1; SMN2 (0.49) | ALDH1A1PDE3BPDE3AKDM4ESMN1; SMN2 | |
| SCHEMBL3350433 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL3345122 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTPDE3B | |
| SCHEMBL5328637 | 0.77 | KDM4E (0.62) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6584194 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |