Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344690 | 0.87 | SMN1; SMN2 (0.49) | KDM4EALDH1A1NR3C1SMN1; SMN2DAO | |
| SCHEMBL3349053 | 0.84 | ALDH1A1 (0.45) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14317182 | 0.81 | NR3C1 (0.40) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3349059 | 0.81 | ALDH1A1 (0.46) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3345086 | 0.80 | ALKBH3 (0.42) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3346093 | 0.80 | ALDH1A1 (0.46) | KDM4EL3MBTL1ALDH1A1MAPTHPGD | |
| SCHEMBL3785180 | 0.78 | KDM4E (0.47) | KDM4EL3MBTL1KMT2AMEN1HTT | |
| SCHEMBL15931678 | 0.77 | KDM4E (0.38) | KDM4EHTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3349142 | 0.76 | ALDH1A1 (0.53) | KDM4EKMT2AMEN1ALDH1A1DAO | |
| SCHEMBL3345122 | 0.75 | ALDH1A1 (0.43) | KDM4EKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |