Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349142 | 0.84 | ALDH1A1 (0.53) | KDM4EALDH1A1CYP1A2DAO | |
| SCHEMBL3345086 | 0.81 | ALKBH3 (0.42) | SMN1; SMN2RXFP1ALKBH3ALOX5PTGES | |
| SCHEMBL3349053 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2PDE3BPDE3AALKBH3PTGS2 | |
| SCHEMBL3349059 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2PDE3BPDE3AALKBH3ALOX5 | |
| SCHEMBL3351444 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2RXFP1PDE3BPDE3AALKBH3 | |
| SCHEMBL14246752 | 0.78 | DAO (0.45) | ALOX5KDM4EALDH1A1DAONR3C1 | |
| SCHEMBL14317182 | 0.78 | NR3C1 (0.40) | SMN1; SMN2KDM4EALDH1A1DAONR3C1 | |
| SCHEMBL5326909 | 0.76 | RXFP1 (0.70) | SMN1; SMN2RXFP1KDM4EALDH1A1 | |
| SCHEMBL3350433 | 0.76 | ALDH1A1 (0.43) | ALKBH3PTGS2KDM4EALDH1A1DAO | |
| SCHEMBL14246738 | 0.74 | LMNA (0.48) | SMN1; SMN2ALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |