Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.67 |
| ▸ | MPL | P40238 | 7/20 | 0.59 |
| ▸ | CTRC | Q99895 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.52 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | ATIC | P31939 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amaranth SCHEMBL108344 | 0.90 | THRB (1.00) | THRBMEN1KMT2ATDP1CTRB1 | |
| Amaranth SCHEMBL29371627 | 0.90 | THRB (1.00) | THRBMEN1KMT2ATDP1CTRB1 | |
| Amaranth SCHEMBL185414 | 0.90 | THRB (1.00) | THRBMEN1KMT2ATDP1CTRB1 | |
| Amaranth SCHEMBL344622 | 0.90 | THRB (1.00) | THRBMEN1KMT2ATDP1CTRB1 | |
| Amaranth SCHEMBL31222692 | 0.90 | THRB (1.00) | THRBMEN1KMT2ATDP1CTRB1 | |
| Amaranth SCHEMBL4807654 | 0.89 | THRB (0.98) | THRBMEN1KMT2ATDP1CTRB1 | |
| Amaranth SCHEMBL185412 | 0.89 | THRB (0.98) | THRBMEN1KMT2ATDP1CTRB1 | |
| SCHEMBL8947271 | 0.89 | THRB (0.78) | THRBMEN1KMT2ATDP1CTRB1 | |
| Amaranth SCHEMBL9577797 | 0.89 | THRB (0.98) | THRBMEN1KMT2ATDP1CTRB1 | |
| Amaranth SCHEMBL473254 | 0.89 | THRB (0.98) | THRBMEN1KMT2ATDP1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010055371-A1 | MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES | PICHLER CHRISTIAN (AT) | 2010-05-20 | — | — | WO | claimed |
| WO-2010055371-A1 | MEDICAMENT FOR INHIBITING THE SYNTHESIS OF LEUKOTRIENES | PICHLER CHRISTIAN (AT) | 2010-05-20 | — | — | WO | disclosed |