SCHEMBL8947271

SCHEMBL8947271

Cc1ccc2c(/N=N/c3ccc(S(=O)(=O)O)c4ccccc34)c(O)c(S(=O)(=O)O)cc2c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.78
MEN1 O00255 1/20 0.78
KMT2A Q03164 1/20 0.78
TDP1 Q9NUW8 1/20 0.78
ALDH1A1 P00352 3/20 0.66
HIF1A Q16665 3/20 0.66
CYP1A2 P05177 4/20 0.61
CTRB1 P17538 1/20 0.56
MPL P40238 6/20 0.54
ENPP2 Q13822 2/20 0.48
CTRC Q99895 1/20 0.48
ATIC P31939 1/20 0.45
NSD2 O96028 1/20 0.45
MMP14 P50281 1/20 0.45
CASP6 P55212 1/20 0.45
PHLPP2 Q6ZVD8 1/20 0.44
CYP2C9 P11712 1/20 0.44
TSHR P16473 1/20 0.44
PTPRA P18433 1/20 0.44
PTPRB P23467 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3349622 0.89 THRB (0.82) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL108344 0.87 THRB (1.00) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL185414 0.87 THRB (1.00) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL344622 0.87 THRB (1.00) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL31222692 0.87 THRB (1.00) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL29371627 0.87 THRB (1.00) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL185412 0.86 THRB (0.98) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL4807654 0.86 THRB (0.98) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL9577797 0.86 THRB (0.98) THRBMEN1KMT2ATDP1ALDH1A1
Amaranth SCHEMBL473254 0.86 THRB (0.98) THRBMEN1KMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 US disclosed
US-8932370-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2015-01-13 US disclosed
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-11-06 US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 US disclosed
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2014-01-16 US disclosed
US-8444715-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2013-05-21 US disclosed
US-8419176-B2 Aqueous compositions with improved silicon corrosion characteristics EASTMAN KODAK COMPANY (US) 2013-04-16 US disclosed
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2012-11-01 US disclosed
US-8187340-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2012-05-29 US disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 US disclosed
US-20100302292-A1 AQUEOUS COMPOSITIONS WITH IMPROVED SILICON CORROSION CHARACTERISTICS EASTMAN KODAK COMPANY 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120272990-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 THRB 4668/4885MEN1 3187/4885KMT2A 1622/4885
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 THRB 4668/4885MEN1 3187/4885KMT2A 1622/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 THRB 4668/4885MEN1 3187/4885KMT2A 1622/4885
US-20140013520-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 THRB 4668/4885MEN1 3187/4885KMT2A 1622/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 THRB 4668/4885MEN1 3187/4885KMT2A 1622/4885
US-20140326269-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 THRB 4668/4885MEN1 3187/4885KMT2A 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.