Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349847 | 0.89 | MC4R (0.58) | TAAR1GLAALDH1A1ROCK2MC4R | |
| SCHEMBL3353041 | 0.88 | CNR1 (0.55) | CNR1TAAR1GLAALDH1A1ROCK2 | |
| SCHEMBL3353136 | 0.85 | TAAR1 (0.50) | CNR1TAAR1GLAALDH1A1MC4R | |
| SCHEMBL3353044 | 0.84 | KCNH2 (0.46) | CNR1TAAR1GLAALDH1A1ROCK2 | |
| SCHEMBL22179089 | 0.83 | MC4R (0.63) | CNR1TAAR1GLAALDH1A1MC4R | |
| SCHEMBL22179092 | 0.83 | MC4R (0.63) | CNR1TAAR1GLAALDH1A1MC4R | |
| Hydrochloric Acid SCHEMBL22160598 | 0.82 | MC4R (0.61) | CNR1TAAR1GLAALDH1A1MC4R | |
| SCHEMBL3353112 | 0.79 | MC4R (0.43) | CNR1TAAR1GLAALDH1A1ROCK2 | |
| SCHEMBL3346447 | 0.78 | MC4R (0.63) | DPP4TAAR1GLAALDH1A1MC4R | |
| Hydrochloric Acid SCHEMBL28630359 | 0.77 | MC4R (0.55) | CNR1TAAR1GLAALDH1A1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |