Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.44 |
| ▸ | KDM5A | P29375 | 5/20 | 0.44 |
| ▸ | KDM5C | P41229 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.44 |
| ▸ | KDM4A | O75164 | 4/20 | 0.44 |
| ▸ | KDM6B | O15054 | 3/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TET3 | O43151 | 1/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811985 | 0.81 | PROKR1 (0.49) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL30505322 | 0.81 | PROKR1 (0.49) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL11340185 | 0.77 | KDM4E (0.55) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| Hydrochloric Acid SCHEMBL15973575 | 0.76 | KDM4E (0.53) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL3346038 | 0.75 | TTR (0.35) | KDM4EALDH1A1EGLN1 | |
| SCHEMBL3478647 | 0.73 | HCAR3 (0.43) | KDM4D | |
| SCHEMBL7875993 | 0.73 | HCAR3 (0.43) | KDM4D | |
| SCHEMBL24473745 | 0.72 | KDM5B (0.50) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL26910750 | 0.72 | KDM4C (0.49) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL21104531 | 0.71 | KMT2A (0.46) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |