Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 11/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3478647 | 1.00 | HCAR3 (0.43) | HCAR3BACE1KDM4D | |
| SCHEMBL3346038 | 0.78 | TTR (0.35) | BACE1 | |
| SCHEMBL7880801 | 0.76 | BACE1 (0.64) | BACE1 | |
| SCHEMBL2210348 | 0.76 | BACE1 (0.64) | BACE1 | |
| SCHEMBL3853328 | 0.75 | HCAR3 (0.45) | HCAR3BACE1 | |
| SCHEMBL3857905 | 0.75 | HCAR3 (0.45) | HCAR3BACE1 | |
| SCHEMBL3860002 | 0.74 | HCAR3 (0.44) | HCAR3BACE1 | |
| SCHEMBL3855704 | 0.74 | HCAR3 (0.44) | HCAR3BACE1 | |
| SCHEMBL3350177 | 0.73 | KDM4C (0.44) | KDM4D | |
| SCHEMBL7946697 | 0.72 | BACE1 (0.34) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |